EVAg

The AAV8 expresses an anti-CD8 targeting antibody (clone YTS169) allowing long-term depletion of CD8 T cells. The isotope of the depletion antibody is a mouse IgG2a.

The AAV8 expresses an anti-CD20 targeting antibody (clone 18B12) allowing long-term depletion of B cells. The isotope of the depletion antibody is a mouse IgG2a.

Plasmid encoding the AAV-aVSVG. The AAV-aVSVG expresses a VSVG targeting antibody.

Plasmid encoding the AAV-ST2-Fc. The AAV-ST2-Fc allows blockade of IL-33 signalling.

Plasmid encoding the AAV-aGr-1. The AAV-aGr-1 allows depletion of neutrophils and myeloid cells.

Plasmid encoding the AAV-aNK1.1. The AAV-aNK1.1 allows long-term depletion of NK cells.

Plasmid encoding the AAV-aCD4. The AAV-aCD4 allows long-term depletion of CD4 T cells.

The AAV8 expresses the VI10 antibody targeting the glycoprotein of vesicular stomatitis virus. It can be used as a control for depletion-AAVs. The isotope of the antibody is a mouse IgG2a.

The AAV8 expresses a soluble ST2 (IL-33 receptor) coupled to the Fc part of an IgG1a antibody, allowing the blockade of IL-33 signalling.

The AAV8 expresses an anti-Gr-1 targeting antibody (clone RB6.8C5) allowing the depletion of neutrophils and other myeloid cells. The isotope of the depletion antibody is a mouse IgG2a.

The AAV8 expresses an anti-NK1.1 targeting antibody (clone PK136) allowing the long-term depletion of NK cells. The isotope of the depletion antibody is a mouse IgG2a.

The AAV8 expresses an anti-CD4 targeting antibody (clone YTS191) allowing the long-term depletion of CD4 T cells. The isotope of the depletion antibody is a mouse IgG2a.

Plasmid encoding the AAV-aCD20. The AAV-aCD20 allows long-term depletion of B cells.

Plasmid encoding the AAV-aCD8. The AAV-aCD8 allows long-term depletion of CD8 T cells.

Freeze-dried Chikungunya virus, strain UVE/CHIKV/2024/RE/CNR_79903, La Réunion 2024, complete genome,

Infectious cell culture supernatant containing SARS-CoV-2 (strain hCoV-19/Slovenia/LP3/10/25; lineage Omicron, LP.8.1). This strain is preserved in viral storage medium -80°C.

Infectious cell culture supernatant containing SARS-CoV-2 (strain hCoV-19/Slovenia/LP3/7/25; lineage Omicron, MC.1). This strain is preserved in viral storage medium -80°C.

In vitro transcribed RNA for Wuhan coronavirus (2019-nCoV) real time (RT-)PCR targeting region of the RdRP gene . Protocol and preliminary evaluation for this assays (Corman/Drosten 2020), as of Jan 13, 2020, available from: https://www.who.int/docs/default-source/coronaviruse/protocol-v2-1.pdf?sfvrsn=a9ef618c_2 Ref: https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2020.25.3.2000045

In vitro transcribed RNA for Wuhan coronavirus (2019-nCoV) real time (RT-)PCR targeting region of the E gene . Protocol and preliminary evaluation for this assays (Corman/Drosten 2020), as of Jan 13, 2020, available from: https://www.who.int/docs/default-source/coronaviruse/protocol-v2-1.pdf?sfvrsn=a9ef618c_2 Ref: https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2020.25.3.2000045

Purified RNA of SARS-Coronavirus strain Frankfurt 1, grown in cell culture. Dislaimer: Import permit maybe be needed in your country for the SARS-CoV full virus RNA. If yes, please indicate so in your online enquiry.

Extracted RNA of Human coronavirus 229E isolate HCoV-229E/BN1/GER/2015

Recombinant Hendra virus 1994 expressing GFP

Freeze-dried Dengue virus 2, strain UVE/DENV-2/2023/MQ/CNR_65244, Martinique 2023, complete genome,

Frozen Enterovirus A71, strain UVE/EV-A71/2019/FR/0622 , France 2019, complete ORF sequence.

Freeze dried Chikungunya virus, strain UVE/2023/BR/CNR_65248, Brazil 2023, complete genome sequence.