- Tagged as
- - Antigen
- - Diagnostic reagent
- - Virus
- - Cultivable virus
Produced by
: ERASMUS-MC Shipping From
: Rotterdam - NL
Product Description
Ref-SKU:
011V-02855 This isolate belongs to a unique set of HSV-1 isolates cultured from corneal swabs taken from deceased corneas of otherwise healthy immunecompetent patients with a history of recurrent HSV-1 keratitis in The Netherlands. In-vitro susceptibility profile, and thymidine kinase genotype, have been described for acyclovir, ganciclovir and foscarnet.
Product Risk Group:
ICTV Taxonomy:
Virus name:
Subspecies:
Isolate:
Storage conditions:
Viral Storage Medium -80C
Sequencing:
Partial sequence
Infectivity:
Infectivity tested
Mycoplasmic content:
Not tested
Special feature:
GMO:
No
Biosafety restrictions:
BSL2
Virus host type:
Previous Name or Taxonomy:
Infectivity Test:
: virus stocks generated in Vero cells. Virus production in culture supernatant was tested by HSV-1 specific PCR and HSV-specific immunefluorescence on infected Vero cells.
Production cell line:
Genbank reference:
Virus Cultivability:
Passage:
5-7
Identification technique:
HSV-1-specific qPCR
Shipping conditions:
IATA Classification:
Note:
Isolate #R7 is acyclovir-resistant, but ganciclovir and foscarnet sensitive (see PMID: 19795980)
Information about the collection of the virus
Recombinant product:
No
Biological material origin:
Natural origin
Collection date:
Monday, 1 January, 2018
Country of collection:
Suspected epidemiological origin :
Isolation host:
Isolation technique:
virus culture in-vitro
Isolation conditions:
infection of Vero cells with aliquot virus transport medium containing corneal swab.
Clinical information:
otherwise healthy immunecompetent patient with recurrent HSV-1 keratitis