List of ERASMUS-MC's EVAg products

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This page lists the ERASMUS-MC's EVAg products. The additional filters enable you with creating a sub-selection of items of this list. The search engine above will seek products into the complete catalogue.

28 products displayed

MERS-CoV single chain antibody HCAb-83

Produced by:

ERASMUS-MC

Shipping From:

Rotterdam - NL

Antibody

Ref-SKU:

011A-02999

HCAb-83 is a MERS-CoV specific camel/human chimeric heavy chain only antibody (HCAb) - composed of the camel VHH-83 linked to a human Fc domain lacking the CH1 exon Through direct cloning and expression of the variable heavy chains (VHHs) of HCAbs from the bone marrow of MERS-CoV infected dromedaries, MERS-CoV specific VHHs or nanobodies were produced. VHH-83 binds with exceptionally high affinity to the receptor binding domain of the viral spike protein. In vitro, HCAb-83 efficiently blocks virus entry at picomolar concentrations

Unit: 50 µg

Riboviria / Orthornavirae / Pisuviricota / Pisoniviricetes / Nidovirales / Cornidovirineae / Coronaviridae / Orthocoronavirinae / Betacoronavirus / Merbecovirus / Middle East respiratory syndrome-related coronavirus

Virus name:

MERS-CoV

500,00 €
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