Scientific Publication:

Live Zika virus chimeric vaccine candidate based on a yellow fever 17-D attenuated backbone

Authors: 
Touret Franck, Gilles Magali, Klitting Raphaelle, Aubry Fabien, de Lamballerie Xavier, Nougairède Antoine
Journal: 
Emerging Microbes & Infections
Date of publication: 
Saturday, 1 December, 2018
Volume: 
7
Issue: 
1
Pages: 
null
Related PMID: 
30254297
Related DOI: 
10.1038/s41426-018-0161-7
EVAg connections: 
Research funded by EVAg
Related to EVAg product
Published by EVAg partner
This publication has been related to the following 1 product(s) of our catalogue

1 products displayed

ISA Reverse Genetic System for chimeric virus CH-17D / ZIKV

Produced by:
AMU
Shipping From:
Marseille - FR
nucleic-acid
Ref-SKU:
001N-03399
Infectious Subgenomic Amplicons Reverse genetic system for chimeric virus CH-17D / ZIKV. It consists of three non infectious overlapping DNA fragments (cloned into pUC57 vector) . These products enable to obtain infectious RNA virus after amplification by PCR, and transfection into susceptible cells. The chimeric virus systems were constructed using the yellow fever 17-D vaccine strain as a genetic backbone and by replacing prM/E from this vaccine strain with those of the Asian ZIKV PF epidemic strain.
Unit: 3 overlapping plasmids
Riboviria / Orthornavirae / Kitrinoviricota / Flasuviricetes / Amarillovirales / Flaviviridae / Flavivirus / Yellow fever virus
Virus name: 
Yellow fever/Zika Chimeric virus
Strain: 
CH-17D / ZIKV


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